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Tramadol is an analgesic thatís been found to be very effective for the treatment of moderate to severe pain. Its mechanism of action is very similar to that of codeine or hydrocodone, except that tramadol is not a narcotic. The federal government does not include tramadol as a controlled substance ounder the guidelines set forth in the federal Controlled Substances Act.
Tramadol acts within the central nervous system, binding to receptors throughout the brain called Mu receptors. These Mu receptors are responsible for the perception of pain. Tramadol also has an antidepressant effect because it is a selective serotonin reuptake inhibitor. Serotonin is a neurotransmitter thatís responsible for an individualís sense of psychological wellbeing. When serotonin is in short supply, an individual feels depressed. By increasing the amount of circulating serotonin within an individualís bloodstream, tramadol helps that individual combat depression. Numerous studies have found that people experiencing chronic pain can easily become depressed, so tramadolís effects in this regard are very therapeutic.
Generic tramadol is usually supplied as a 50 mg tablet. The recommended dose for acute pain is 50 to 100 mg of tramadol (one or two tablets) taken every four to six hours to control pain. You should never take more than 400 mg of tramadol (eight tablets) in a single day, however: Tramadol is known to decrease the brainís seizure threshold significantly and high doses may precipitate seizures.